Research

I am an Assistant Professor in the Department of Mathematics at the University of British Columbia, and associate member of the Departments of Computer Science and Zoology.

My research group combines mathematical, computational and statistical tools to study fundamental biological processes (for more details, see my publications). We are currently mostly  focusing on studying the properties of the ribosome across scales and system (NSERC Discovery grant RGPIN-2020-05348), and developing new algorithms for  Cryo-EM data (New Frontiers of Research NFRFE-2019-00486)

My CV is available here


NEWS:

  • To Students: M.Sc, PhD and Postdoc positions are available. Students can choose to be affiliated with the math, computer science, or zoology departments and graduate programs at UBC, and work on a broad range of interdisciplinary research problems, in collaboration with other groups and labs in Canada, United States, France, Israel, or China. Topics of research include 
    • development of mathematical and computational methods for cryo-EM
    • development of bioinformatics tools and database for Ribosome 3D structures
    • modelling and analysis of gene expression
    • biophysical simulations of polymer/intracellular transport
    • stochastic modelling and analysis of biological processes
    • mathematical and computational neuroscience.
      For more details, feel free to contact me.
  • Our ChimeraX plugin for transport-based interpolation between cryo-EM maps is available: Preprint,  GitHub link

morph

  • Our review paper on ribosome heterogeneity and cryo-EM has been published in Molecules special issue: Frontiers in RNA Structure: link
  • Our paper on using the hydrodynamic limit of TASEP to study protein translation has been published in Cell Systems: link, ArXiv (free access, limited in time, here)
  • Our paper on comparative analysis of the ribosome exit tunnel across species has been published in Nucleic Acids Researchlink, f1000 recommendation

ecoli_rRNA_conserved