Research

I am an Assistant Professor in the Department of Mathematics at the University of British Columbia, and associate member of the Departments of Computer Science and Zoology.

My research group combines mathematical, computational and statistical tools to study fundamental biological processes (for more details, see my publications). We are currently mostly  focusing on studying the properties of the ribosome across scales and system (NSERC Discovery grant RGPIN-2020-05348), and developing new algorithms for  Cryo-EM data (New Frontiers of Research NFRFE-2019-00486)

My CV is available here


NEWS:

  • Congratulations to Jules Mirone, Nicolas Legendre and Clément Soubrier for being awarded a PIMS France-Canada fellowship!
  • I will join the Wall Scholars program in 2021-22: https://pwias.ubc.ca/announcements/2021-wall-scholars-announced
  • Our database of ribosomes 3D structures is available online and still under development. Feel free to contact us if you have some feedback and/or are interested to learn more about it: link
  • Our ChimeraX plugin for transport-based interpolation between cryo-EM maps has been accepted in Bioinformatics. Congratulations Arthur Ecoffet for the amazing work! Preprint,  GitHub link

morph

  • Our review paper on ribosome heterogeneity and cryo-EM has been published in Molecules special issue: Frontiers in RNA Structure: link
  • Our paper on using the hydrodynamic limit of TASEP to study protein translation has been published in Cell Systems: link, ArXiv (free access, limited in time, here)
  • Our paper on comparative analysis of the ribosome exit tunnel across species has been published in Nucleic Acids Researchlink, f1000 recommendation

ecoli_rRNA_conserved