My general interest is to combine mathematical, computational and statistical tools to study fundamental biological processes (for more details, see my publications).
For the past few years, I have mostly focused on studying the regulation and determinants of gene expression and translation. To do so, I have developed mathematical models of translation and analyzed data from Ribosome profiling and Cryo-EM structures, while tackling theoretical and computational problems related to particle processes, evolution, and biophysical and molecular properties of the ribosomes.
My CV is available here
- To Students: M.Sc and PhD positions are available. Students can choose to be affiliated with the math, computer science, or zoology departments and graduate programs at UBC, and work on a broad range of interdisciplinary research problems, in collaboration with other groups and labs in Canada, United States, France, Israel, or China. Topics of research include modelling and analysis of gene expression, statistical analysis and machine learning for sequencing/cryo-EM data, biophysical simulations of polymer/intracellular transport, stochastic modelling and analysis of biological processes, mathematical and computational neuroscience. For more details, feel free to contact me.
- Our paper on using the hydrodynamic limit of TASEP to study protein translation has been published in Cell Systems: link, ArXiv (free access, limited in time, here)
- Our paper on comparative analysis of the ribosome exit tunnel across species has been published in Nucleic Acids Research: link, f1000 recommendation